If you're asking what to do for hemorrhoids that disrupt your day, turn to Preparation H Multi-Symptom Pain Relief Cream. Among over the counter brands, it is the only hemorrhoidal cream with maximum strength pramoxine for multi-symptom hemorrhoid relief. Apply up to four times daily for rapid hemorrhoid pain relief that can help you get back to what you want or need to do. Hemorrhoids can flare-up at any time with a variety of symptoms including anus itching, burning, pain and discomfort. In fact, 75% of American men and women experience symptoms of hemorrhoids in their lifetime. While symptoms and number of flare-ups can vary from person to person, Preparation H Multi-Symptom Pain Relief Cream rapidly relieves external hemorrhoid discomfort. The smooth, cream formula is a unique blend with vitamin E, panthenol and soothing aloe to provide comfortable hemorrhoid treatment. And for better relief, use Preparation H Medicated Wipes to cool, soothe and cleanse before treating with Preparation H maximum strength cream. (1) Provoice survey dated from May 2015-August 2017 supports Preparation H is the #1 doctor recommend brand. Made in US Adults: When practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before applying cream. When first opening the tube, puncture foil seal with top end of cap. Apply externally or in the lower portion of the anal canal only. Apply externally to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement. For application in the lower anal canal: remove cover from dispensing cap. Attach dispensing cap to tube. Lubricate dispensing cap well, then gently insert dispensing cap partway into the anus. Thoroughly cleanse dispensing cap after each use and replace cover. Children under 12 years of age: ask a doctor ©GSK group of companies or its licensor