A biologically active methylated folate supplement for reproductive health and fetal development.  Our 5 MTHF supplement contains the most abundant form of folate found in the body. Folate is recommended by the CDC and ACOG for all women of childbearing age to reduce the risk of spina bifida and other neural tube defects. Each tablet contains 1,000 mcg (1 mg) of folate to support fertility and pregnancy outcomes.‡