Advantage Multi (Advocate) for Dogs - Flea and Heartworm Treatment Advantage Multi (Advocate) is a monthly topical spot-on treatment for dogs. This powerful product aids in thecontrol of fleas, heartworm, gastrointestinal worms (hookworms, roundworms, and whipworms). Besides, it treatssarcoptic mange, demodicosis, and ear mite infestations. This solution kills98-100% of adult fleas within 12 hours of application. Advantage Multi (Advocate) for Dogs Imidacloprid and Moxidectin are the two active ingredients present in Advantage Multi. Both these powerful ingredients aid in the thorough elimination of parasites such as gastrointestinal, fleas, and heartworm prevention. It also provides month-long protection for your dogs.