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<h5>Product Description</h5>
<h4>Description</h4>
<p>Heartgard Plus Chew for Dogs is a delicious, once-a-month, real-beef chew that dogs love. Heartgard Plus is a preventative that kills heartworms and also helps treat and control roundworms and hookworms for 30 days. Your furry friend should be tested for existing heartworm infection before starting treatment with HEARTGARD Plus which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with HEARTGARD Plus.</p>
<p>Heart-gard</p>
<h4>Benefits</h4>
<ul>
<li>HEARTGARD Plus attacks heartworm larvae before they can grow into adults and cause heartworm disease.</li>
<li>Year-Round Protection, When given every 30 days, HEARTGARD Plus keeps your dog protected from heartworm disease.</li>
<li>HEARTGARD Plus prevents heartworm disease in dogs as young as 6 weeks of age with no minimum weight requirement.</li>
</ul>
<p><strong><em>Consult with your veterinarian for proper dosage and course of treatment.</em></strong></p>
<h5>Safety Information</h5>
<h4>Warnings</h4>
<p>HEARTGARD Plus has been shown to be bioequivalent to HEARTGARD, with respect to the bioavailability of ivermectin. The dose regimens of HEARTGARD Plus and HEARTGARD are the same with regard to ivermectin (6 mcg/kg). Studies with ivermectin indicate that certain dogs of the Collie breed are more sensitive to the effects of ivermectin administered at elevated dose levels (more than 16 times the target use level) than dogs of other breeds. At elevated doses, sensitive dogs showed adverse reactions which included mydriasis, depression, ataxia, tremors, drooling, paresis, recumbency, excitability, stupor, coma and death.</p>
<h4>Precautions</h4>
<p>All dogs should be tested for existing heartworm infection before starting treatment with HEARTGARD Plus which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with HEARTGARD Plus. While some microfilariae may be killed by the ivermectin in HEARTGARD Plus at the recommended dose level, HEARTGARD Plus is not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermectin alone after treatment of some dogs that have circulating microfilariae.</p>
<!-- <h6>Food and Drug Interactions</h6>
<p>Vetmedin is indicated for use with concurrent therapy for congestive heart failure (e.g., furosemide, etc.) as appropriate on a case-by-case basis. </p> -->
<h4>Human Warnings</h4>
<p>In case of ingestion by humans, clients should be advised to contact a physician immediately. Physicians may contact a Poison Control Center for advice concerning cases of ingestion by humans.</p>
<h5>Side Effects</h5>
<h6>Possible Side Effects</h6>
<p>In clinical field trials with HEARTGARD Plus, vomiting or diarrhea within 24 hours of dosing was rarely observed (1.1% of administered doses). The following adverse reactions have been reported following the use of HEARTGARD: Depression/lethargy, vomiting, anorexia, diarrhea, mydriasis, ataxia, staggering, convulsions and hypersalivation.</p>
<p><strong><em>Contact your veterinarian if you believe your pet is experiencing side effects.</em></strong></p>
<h5>Additional Information</h5>
<h6>Product Administration</h6>
<p>Oral</p>
<h6>Product Form</h6>
<p>Chewable Tablet</p>
<h6>Ingredients</h6>
<p>Ivermectin and pyrantel</p>
<h6>Storage</h6>
<p>Store between 68°F - 77°F (20°C - 25°C). Excursions between 59°F - 86°F (15°C - 30°C) are permitted. Protect product from light.</p>
<h6>Manufacturer</h6>
<p>Boehringer Ingelheim Animal Health USA Inc.</p>
<h6>Prescribing Info/Brochures</h6>
<ul>
<li><a href="https://heartgard.com/sites/default/files/2021-01/2020_HG_Plus_PI_BI.pdf" target="_blank">https://heartgard.com/sites/default/files/2021-01/2020_HG_Plus_PI_BI.pdf</a></li>
</ul>
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