Magnolia Bark Extract Benefits and Uses In its traditional use, Hou pu is typically referred to as having properties to prevent the stagnation of Qi (pronounced “Chi”, meaning life-force) in the abdomen and in the chest. Today, researchers are exploring the effects of Magnolol and Honokiol on 5-HT serotonin receptors, on catecholamines, and on the GABAergic system. It is also used in research for its potential effects on bacteria in the mouth and for its effects on PPAR-γ receptors. While Magnolia Bark Extract is anecdotally reported to be effective, the significance of its benefits will not be fully understood until further research becomes available. Magnolia Bark supplements are also known by a few different names, including: Houpu Beaver Tree Bourgeon Floral de Magnolia Buergeria salicifolia Houpu magnolia Magnolia officinalis 4-Allyl-2-(5-allyl-2-hydroxy-phenyl)phenol (S)-(-)-tetrahydropalmatine 2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol Saiboku-to Hou Pu Chuan Houpu Cortex Magnoliae Officinalis Scientific Consensus Using this supplement at the recommended serving size is likely safe for most adults and has been topically in clinical studies for up to a year. Further research is necessary to fully understand the effects, benefits, and side effects in humans. Magnolia bark extract may interact with alcohol and other medications. DO NOT EXCEED THE RECOMMENDED SERVING SIZE. Use with caution. Do not use if pregnant or breastfeeding. Warning: Supplementing during pregnancy is NOT SAFE. Magnolia bark contains compounds that may be unsafe for pregnant and nursing women. DO NOT take Magnolia bark extract before surgery as it may affect the drugs used for sedation