The XWFE filter replaces the XWF filters and is compatible with all refrigerators that use XWF, including select GE side-by-side and bottom freezer refrigerators.   Premium Filtration：These filters are certified to reduce chlorine-resistant cysts, lead, select pharmaceuticals, and 50 other impurities often found in water. Pharmaceuticals Reduction：Our filter reduces select pharmaceuticals from water, including ibuprofen, progesterone, atenolol, trimethoprim, and fluoxetine*. (*Impurities not necessarily found in all users’ water.) Easy Filter Replacement：You don’t need any tools or to turn off the water to replace these cartridge filters inside your refrigerator. Six-Month Filter Life：For best filtration results, filter cartridge should be replaced every six month or 170 gallons of water filtration.