OBAGI NU-DERM BLEND FX OVERVIEW A gentle formula with arbutin and antioxidants to help clarify and brighten skin. Obagi Nu-Derm Blend Fx is a brightening cream specially formulated with Arbutin, antioxidants and an exfoliant to help clarify and brighten skin. KEY INGREDIENTS ARBUTIN - Nature-identical skin brightening agent and antioxidant. This ingredient can help to prevent and visibly diminish the appearance of uneven skin tone, leading to a more even complexion. HOW DO I USE OBAGI NU-DERM BLEND FX? Apply affected area twice daily or as directed by a physician.