Shipping restrictions: This item cannot ship to California Colistin Sulfate 5% Powder effectively aids in the prevention and treatment of E.coli, Salmonella (Paratyphoid), and respiratory infections in pigeons, cage & aviary birds, and backyard poultry. Colistin may be used as the last-resort treatment when battling a gram-negative bacterial infection in your birds which may be resistant to other antibiotics and have not successfully worked.  Key Benefits A last-resort treatment and prevention against Salmonella (Paratyphoid), E.coli, and many variations of respiratory infections Multi-bird species formula may be used on pigeons, backyard chickens, and cage/ornamental birds Powder easily dilutes in water One pouch medicates up to 20 gallons of water Resealable pack keep contents fresh, longer Dosage Instructions 1 teaspoon (5 grams) per gallon of water for 5 consecutive days. Change water daily.  Active Ingredient 5g Colistin Sulfate per 100g Size 100 g (3.5 oz) powder in resealable pouch. * Disclaimer: This product is for pet birds only. Not for animals whose meat or eggs are intended for human consumption*