Disclaimer: Select IOPE products feature an additional label overlay to comply with US policies and regulations. Rooted in IOPE Stem III cream the three key ingredients that serve to revitalize tired and aged skin this intense anti-aging cream strengthens the weakened skin's moisture barrier and refreshes tired looking skin with powerful strengthening agents. IOPE's innovative Allanto-Complex, plus niacinamide and aminos are specially developed for calming, anti-aging and reinforcement of skin's moisture barrier. The Allanto-Complex in this moisturizing cream is composed of three active ingredients for ultimate skin strength: Allantoin: helps calm skin and infuses deep moisture Spiraeoside: helps visibly revitalize complexion Peptides: helps plump and improve the appearance of fine lines and elasticity This cutting-edge ingredient formulation shows improvement in five indicators: The look of skin texture, radiance, moisture level, transparency and amount of dead skin cells. Researched, tested, and clinically-proven, this anti-aging cream is safe for all skin types, with a mild, hypoallergenic formula free of nine irritants including animal ingredients, fragrance and parabens. IOPE Stem III Cream is sustainably packaged, built with a recycled plastic cartridge to refill the product insert as you use it. ***Formulated without animal ingredients, mineral oil, polyacrylamide, imidazolidinyl urea, triethanolamine, synthetic pigment, fragrance, PEG surfactant, and parabens. The pH level of this formula is 6.5±1.0, to ensure optimal potency and support skin health. **Product volume has been increased from 40ml to 50ml 50 ml / 1.69 oz