Food sensitivities and intolerance are potentially serious problems that can result in sensitive or irritated skin, coat and ear conditions or even gastrointestinal upset. Dogs that have food sensitivities or intolerance, also called adverse reactions to food, typically experience an abnormal response to the protein in the food. If your dog suffers from adverse reaction to food, it is even more important to feed the right diet. Hill's nutritionists and veterinarians developed Prescription Diet z/d clinical nutrition especially formulated to support your dog's skin and food sensitivities. In fact, z/d is clinically proven nutrition to help avoid adverse reactions to food. Plus, with the S+OXSHIELD seal of confidence, the Skin/Food Sensitivities formula meets specific nutrient standards shown to promote a urinary environment that helps reduce the risk of struvite and calcium oxalate crystals.