Nature's Logic Center Cut Hind Shank Bone is made from only all-natural, Midwest beef sources and cattle-graded USDA Prime. These delicious treats are great for carnivore-appropriate recreational chewing and for promoting good dental hygiene. Plus, they’re made in the USA without the use of potatoes, peas, lentils, wheat, corn, rice, soy, potato or chemically synthesized vitamins, minerals, trace nutrients, carrageenan, guar gum or xanthan gum.