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Supplement Facts & Directions Supplement Facts Serving Size: 10 milligrams Servings Per Container: Varies Amount Per Serving % Daily Value* Piperine (from Black Pepper Extract) 10 mg † * Percent Daily Values are based on a 2,000 calorie diet. † Daily Value Not Established ‡ These supplement facts may vary from the product you receive. Please call for exact numbers. Other Ingredients: None Contains: Free of: Added Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives. Directions: As a dietary supplement, take 10 mg one to two times per day, or as directed by a physician. An accurate gram weight scale is recommended. Do not exceed recommended serving size. Warning: If you are pregnant, nursing, taking any medications, or have any medical conditions, consult your physician before use. People with diabetes, bleeding disorders, and gastrointestinal disorders need to consult a healthcare professional before use. Piperine may interact with some medications. Keep out of reach of children. Product Details What is Piperine 95% (Black Pepper Extract)? Piperine 95% is an extract that comes from the fruits of the black pepper (Piper nigrum) plant. The extraction process concentrates the active compound, piperine. Piperine is a bioactive alkaloid that is responsible for black pepper’s characteristic piquancy and flavor. It’s also what gives black pepper extract its unique beneficial properties. Ayurvedic cultures use black pepper for several purposes, including as a digestive aid, circulation support, and metabolism stimulant. Black pepper extract is also a potent antioxidant with anti-inflammatory properties. Potential Benefits of Piperine 95% (Black Pepper Extract) Piperine 95% (Black Pepper Extract) Antioxidants Piperine exhibits antioxidant activity, helping neutralize free radicals and reducing markers of free radical damage in the body. Antioxidants are crucial to protect cells from the oxidative stress wrought by an excess of free radicals. Without antioxidants to keep them in check, free radicals can lead to or worsen chronic health issues and expedite the aging process. Piperine 95% (Black Pepper Extract) as an Anti-Inflammatory and Analgesic Piperine extracted from black pepper has anti-inflammatory properties. Long-term oxidative stress promotes inflammation, and piperine may help fight this by protecting cells against free radicals. Animal studies also show that piperine reduces inflammatory biomarkers and joint swelling. Piperine also interacts with the Transient Receptor Potential Vanilloid 1 (TRPV1) receptor that participates in the sensation of heat and pain. In addition to providing inflammatory relief, piperine may act as an analgesic by modulating TRPV1 activity to influence pain perception. Potential Benefits of Piperine (Black Pepper) and Turmeric Piperine can enhance nutrient absorption and improve the bioavailability of some vitamins and minerals by inhibiting enzymes that metabolize nutrients in the digestive tract. Turmeric often has poor absorption alone, but taking black pepper and turmeric together can circumvent this issue. Black pepper extract and turmeric possess antioxidant and anti-inflammatory properties that synergize when taken together to deliver superior results. Black pepper extract can also enhance the absorption of other supplements, including calcium, selenium, and green tea. Potential Side Effects of Piperine 95% (Black Pepper Extract) Black pepper is a popular spice used in everyday cuisine. As such, most people can take black pepper extract without experiencing adverse effects. However, high doses may cause nausea or upset stomach. Individuals with a black pepper allergy should not take black pepper extract. Black pepper extract may interact with certain medications, as it can enhance how the body absorbs and metabolizes them. Individuals taking medications or other supplements should consult a physician before starting any new supplement to avoid unwanted interactions. References https://www.ncbi.nlm.nih.gov/pubmed/23768180 https://www.ncbi.nlm.nih.gov/pubmed/27111639 https://www.ncbi.nlm.nih.gov/pubmed/28230726 https://nccih.nih.gov/health/antioxidants https://www.ncbi.nlm.nih.gov/pubmed/22505880 https://www.ncbi.nlm.nih.gov/pubmed/30531003 https://www.ncbi.nlm.nih.gov/pubmed/27738491 https://www.ncbi.nlm.nih.gov/pubmed/15231065 https://www.ncbi.nlm.nih.gov/pubmed/19327174 https://www.ncbi.nlm.nih.gov/pubmed/23921080 https://www.ncbi.nlm.nih.gov/pubmed/29370858 https://www.sciencedirect.com/science/article/pii/S0308814605009660 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688199 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576058 Tested by Accredited 3rd Party Labs PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity, and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here. *NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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