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Nicotinamide adenine dinucleotide (NAD⁺) is a critical coenzyme found in all living cells. It plays a central role in various biological processes, particularly in energy metabolism and cellular function.
Functions
Energy Metabolism:
NAD⁺ acts as an electron carrier in cellular respiration.
It alternates between its oxidized form (NAD⁺) and reduced form (NADH) during metabolic reactions.
NAD⁺ accepts electrons during glycolysis, the citric acid cycle, and oxidative phosphorylation, driving ATP production.
DNA Repair:
NAD⁺ is a substrate for enzymes like PARPs (poly ADP-ribose polymerases) that repair DNA damage.
Gene Expression Regulation:
It regulates gene expression by serving as a substrate for sirtuins, a class of proteins involved in aging, stress response, and metabolic regulation.
Signal Transduction:
NAD⁺ is involved in calcium signaling and other cellular signaling pathways.
Cellular Aging:
NAD⁺ levels decline with age, contributing to reduced mitochondrial function and increased oxidative stress.
NAD⁺ is indispensable for life, influencing both cellular health and systemic processes. Its role in aging and disease makes it a focus of intense scientific research.
Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.
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