Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone effectively treats acute and chronic otitis externa due to bacterial, fungal and yeast infections. Zymox Otic contains three active enzymes that have shown to be antibacterial, antifungal and antiviral. This three point enzyme system destroys antibiotic resistant microorganisms, including Staphylococcus. The addition of 1% Hydrocortisone helps to provide relief from itching and inflammation. Zymox Otic Pet Ear Treatment with Hydrocortisone acts as both a cleaner and a treatment, in just one application daily.