Parasite Prevention is easier with our award-winning Twist-N-Apply tube. Simply twist the tip to break the seal and apply! No need to remove the cap. **Your pet must have a current heartworm test result on file with your veterinarian to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect them.** Barrier for Dogs® (imidacloprid + moxidectin) Topical Solution is a generic equivalent to Advantage Multi. Barrier for Dogs® is used for the prevention of heartworm disease caused by Diroflaria immitis and the treatment of Diroflaria immitis circulating microfilariae in heartworm-positive dogs. Barrier for Dogs® also kills adult fleas and treats flea infestations (Ctenocephalides felis). Barrier for Dogs® is indicated for the treatment and control of sarcoptic mange caused by Sarcoptes scabiei. It also treats and controls the following intestinal parasite species: Hookworms (Ancylostoma caninum) (Uncinaria stenocephala), Roundworms (Toxocara canis and Toxascaris leonina) and Whipworms (Trichuris vulpis). Our easy Twist-N-Apply tube designs simplifies the application process, eliminating the need to remove the cap. Manufactured and packaged in the USA. **We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer.**