Fast Relief From Fissure Symptoms People searching for an anal fissure medicine are left with few options besides prescriptions or surgery. There may not be a cure for anal fissures, but addressing fissure symptoms at home is actually simple.* Some Tips For Discomfort and Fissure Pain Relief Long term prevention and treatment for anal fissures should include keeping bowel movements soft by changing to a high fiber diet with plenty of water hydration. Protect the anal canal by lubricating it before each bowel movement and use a gentle fragrance-free baby wipe afterward. Discomfort can be relieved by applying ice packs to the area or sitting in a bowl of warm water several times a day to soothe and relax the painful fissure. H-Fissures Formula can be used as soon as symptoms appear. Also, see our hemorrhoids product.*