HEARTGARD® Plus (ivermectin/pyrantel) Chewables for Dogs are the #1 vet-recommended1 protection against heartworm disease – an invisible threat that can be caused by just one bite from an infected mosquito and can lead to permanent damage in less than three months.2 HEARTGARD Plus chews also treat and control 3 species of hookworms and 2 species of roundworms in dogs, which are among the most prevalent intestinal nematode parasites.3 With cases in all 50 states, it’s important to protect your dog with a monthly heartworm preventive year-round.3 Following the use of HEARTGARD Plus chews, digestive and neurologic side effects have been reported. HEARTGARD® Plus chews are also #1 dog-preferred4, making the tasty, Real-Beef chew easy to give your dog for heartworm disease prevention. HEARTGARD Plus is safe to use in all dogs aged 6 weeks and older. Year-round monthly dosing is recommended by the American Heartworm Society as an easy way to protect your dog throughout the year. Ask your veterinarian about preventing heartworm disease in your dog with HEARTGARD Plus chews, and make sure they have a current annual heartworm test result on file.