CVS Health Maximum Strength Double Antibiotic + Pain Relief Cream Neomycin sulfate, 3.5 mg Polymyxin B sulfate USP, 10,000 units Pramoxine HCl USP, 10 mg 1 oz compares to the active ingredients in Neosporin® + Pain Relief Cream. As a maximum strength double antibiotic plus pain reliever, it helps soothe, prevent infection and relieve pain in minor cuts, scrapes and burns. HSA/FSA eligibleDoubles as a maximum strength double antibiotic plus pain relieverHelps soothe, prevent infection and relieve pain in minor cuts, scrapes, and burns