Power up the powerhouse of your cells. Signal is designed to target metabolic aging by protecting mitochondria—where the energy in your cells is made. Increase NAD+ with the precursor NMN to support energy production and activate SIRT3, a key mitochondrial enzyme, to protect and generate new mitochondria and help your cells adapt to daily metabolic changes as you age. Increase levels of the critical coenzyme NAD+ by 40% via the highly efficient precursor NMN Activate sirtuin 3 (SIRT3) to protect and generate new mitochondria to support cellular metabolism and energy Help maintain healthy insulin sensitivity in muscle—essential to maintaining blood sugar levels Support vascular health—critical for your athletic endurance  Support brown fat thermogenesis, a cellular process which converts sugar and fat into heat to help maintain body temperature and support a healthy metabolism Reduce general tiredness and fatigue, support healthy muscle function, and feel good for your age