5% The strongest topical numbing cream sold over-the-counter is lidocaine. After application, it begins to function within two to three minutes and lasts for an hour at its most potent. Rich in vitamin E, this product moisturizes and hydrates your skin while reducing swelling and inflammation. supports itchiness or flaking brought by by dry skin. Our product is developed with child-resistant packaging, is cruelty-free, vegan, non-greasy, odorless, and chemical-free.