2-count Trial of Upneeq® (oxymetazoline hydrochloride ophthalmic solution), 0.1% Upneeq is the first and only FDA-approved eye drop that's been clinically proven to quickly and safely lift low-lying eyelids (also known as acquired ptosis). A fast-acting, nonsurgical way to lift the upper eyelid Results as fast as 5 minutes and can last up to 8 hours Approved for once daily use. Use every day, or days when you want a little lift. How to Order Upneeq requires a prescription, but we offer a convenient option to complete your medical review online with our licensed providers. Just complete the following steps and our online medical providers will evaluate if Upneeq is right for you. Add to cart Log in or create a new account Fill out the required medical intake (takes less than 5 minutes to complete) Upload images of your identification and selfies of your eyes for review Depending on shipping state, you may need to complete a quick video consultation with our medical providers. See shipping restrictions below.