The ingredients in Cortisol Manager support healthy cortisol levels.* Cortisol is one of the most important hormones involved in the adaptation process. By supporting balanced cortisol and a healthy stress response, Cortisol Manager also promotes relaxation to support restful sleep.*THE ROLE OF CORTISOL IN TIMES OF STRESSCortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol homeostasis is typically characterized by peak secretion during the early morning hours with a gradual decline throughout the day. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact.WITH HERBAL INGREDIENTSThe ingredients in Cortisol Manager help support a balanced, adaptive cortisol response to stress.* Cortisol Manager contains a stress-reducing proprietary blend of Sensoril® brand ashwagandha (Withania somnifera) and L-theanine.* A proprietary blend of Magnolia (Magnolia officinalis) and epimedium (Epimedium koreanum), as well as phosphatidylserine from soy lecithin are included in Cortisol Manager.A 2008 placebo-controlled clinical trial showed that Sensoril® ashwagandha significantly reduced serum cortisol levels and helped manage stress compared to placebo, in subjects experiencing higher levels of stress.*1The ingredients in Cortisol Manager help support relaxation to promote restful sleep.* They also help stabilize the stress hormone cortisol to further support a healthy stress response.*REFERENCES Auddy B et al. J Am Nutraceutical Assoc. 2008;11(1):50-6. Nobre AC et al. Asia Pac J Clin Nutr. 2008;17(S1):167-68.